Investigating the role of factor inhibiting HIF (FIH) in tumourigenesis

The tumour microenvironment (TME) is frequently hypoxic and inflammatory, leading to the activation of the Hypoxia-Inducible Factor (HIF) family of transcription factors. HIF has been shown to exert broad, and sometimes controversial, effects on tumour progression through the induction of over 70 ef...

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Bibliographic Details
Main Author: Ma, Jingyi
Other Authors: Ratcliffe, Peter J. ; Lu, Xin
Published: University of Oxford 2017
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.748778