Dissecting domain-specific functions of the IGF2/M6P receptor
The P-type lectin Mannose 6-phosphate/Insulin-like growth factor 2 receptor (M6P/IGF2R) is a type I trans-membrane protein with 15 homologous extracellular domains that bind several ligands. While domains 3, 5 and 9 bind to Mannose 6-Phosphate (M6P), domain 11 binds to IGF2 (Insulin-like growth fact...
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University of Oxford
2016
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.748653 |