Yeast genome-wide telomere screens and insights into cancer
Telomeres are the very ends of linear eukaryotic chromosomes and when too short or dysfunctional they can trigger senescence (ageing). If the cell can bypass senescence, it can lead to genetic instability or cancer. Telomere capping proteins such as the CST (Cdc13, Stn1 and Ten1) complex and Yku70 a...
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University of Newcastle upon Tyne
2017
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.748160 |