New approaches to Pictet-Spengler-type cyclisation reactions

A modified Pictet–Spengler synthesis has been developed, which alleviates the problems associated with the classical synthesis. A-methoxyurethanes were used as precursors, and cyclisation initiated under mild Lewis acid conditions in non-aqueous media at room temperature. Precursors with unactivated...

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Bibliographic Details
Main Author: Cheung, Gi-Kwong
Published: Loughborough University 1993
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.747850