Molecular characterisation of childhood craniopharyngioma and identification and testing of novel drug targets

BACKGROUND: Adamantinomatous Craniopharyngiomas (ACPs) are clinically challenging sellar region tumours, known to be characterised by mutations in CTNNB1. ACPs are often histologically complex, with different morphological cell types and surrounded by a florid glial reaction. Murine models have been...

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Bibliographic Details
Main Author: Apps, John Richard
Published: University College London (University of London) 2018
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Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.747409