CAR gene transfer to generate antigen specific regulators

Adoptive transfer of antigen specific regulatory T (Treg) cells was shown to be beneficial for the suppression of autoimmunity. In this study, we engineered antigen-specific Treg-like cells that recognise mouse MHC-class II molecules. The restricted expression of MHCII to professional antigen presen...

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Bibliographic Details
Main Author: Stavrou, M.
Other Authors: Stauss, H. ; Pule, M. ; Shlomchik, W.
Published: University College London (University of London) 2016
Subjects:
616
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.746216