Synthesis of analogues of epibatidine based on the 2-azabicyclo[2.2.1]heptane system

Epibatidine (exo-2-(6-chloro-3-pyridyl)-7-azabicyclo[2.2.1]heptane) is an alkaloid isolated from the skin of the Ecuadorian poison frog. It has been known since 1992 and has high binding affinity for nicotinic acetylcholine receptors. Many studies have reported epibatidine to possess analgesic prope...

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Bibliographic Details
Main Author: Al-Rubaye, Huda Ismail
Other Authors: Handa, Sandeep
Published: University of Leicester 2018
Subjects:
540
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.745849