In-silico guided prediction of allosteric sites on proteins : application to cyclin-dependent kinase 2

Allostery is the functional change at one site on a protein caused by a change at a distant site. Despite being discovered more than 50 years ago allostery has remained a mystery, and there is no unified scheme to understand and predict it. In order for the the benefits of allostery to be taken adva...

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Bibliographic Details
Main Author: Greener, Joe
Other Authors: Sternberg, Michael
Published: Imperial College London 2017
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.745272

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