Investigating the role of Rho Kinase (ROCK) in the wall of the embryonic and adult heart

Investigating the role of Rho Kinase (ROCK) in the wall of the embryonic and adult heart

Congenital heart defects are relatively common, affecting over 1% of live births, while adult heart disease is the main cause of death in the UK. Defects acquired during fetal development can have a lasting detrimental effect on adult heart function. Therefore, understanding the underlying mechanism...

Full description

Bibliographic Details
Main Author:	Bailey, Kate Elizabeth
Other Authors:	Phillips, Helen ; Henderson, Deborah
Published:	University of Newcastle upon Tyne 2016
Subjects:	616.1
Online Access:	https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.743386

Similar Items

The role of the transcription factor MAD4 in embryonic haematopoiesis
by: Boros, Katalin
Published: (2009)

Survival and risk factors for mortality among individuals with congenital heart disease
by: Best, Kate Elizabeth
Published: (2016)

Investigations into the role of phosphoinositide 3-kinase (P13K) in platelet priming and antiplatelet resistance
by: Blair, Thomas Anthony
Published: (2015)

The role of delta-like 1 in the mouse embryonic haematopoietic stem cell microenvironment
by: Mirshekar-Syahkal, Bahar
Published: (2010)

The right ventricle in adult congenital heart disease
by: Plymen, C. M.
Published: (2014)

Mechanisms of the chronic heart failure syndrome in adults with congenital heart disease and their prognostic value
by: Dimopoulos, Konstantinos
Published: (2009)

Experimental and numerical investigation of arterial wall mass transport
by: Chooi, Kok Yean
Published: (2015)

Investigation of sphingosine-1-phosphate and its analogue FTY720 signalling and their functional roles in the heart
by: Egom, Emmanuel Eroume A.
Published: (2009)

Left ventricular systolic function and myocardial wall stress in conditions predisposing to diastolic heart failure
by: Gu, Haotian
Published: (2017)

On the role of prelamin A in the heart
by: Brayson, Daniel James
Published: (2014)

The role of myocardial glycogen in the ischaemic heart
by: Chao, Feng Zhi
Published: (1998)

Investigation of the genetic basis of coronary heart disease
by: Meng, Weihua
Published: (2008)

Characterisation of a RhoBTB3 deficient mouse model
by: Lutz, Julia Babette
Published: (2012)

Understanding psychological processes in determining outcomes for adults with congenital heart disease
by: Mills, Rónán
Published: (2016)

The role of prostanoids and kinins in the pharmacotherapy of heart failure
by: Davie, Andrew P.
Published: (2000)

The role of Extracellular-Regulated Protein Kinase 2 (ERK2) in cardiac hypertrophic remodelling
by: Ulm, Susanne
Published: (2013)

An investigation into factors associated with compliance with the Heart Manual Cardiac Rehabilitation Programme
by: Cormack, Elinor
Published: (2004)

Patient knowledge and its role in the management of coronary heart disease
by: Anwar, Yasmin
Published: (2010)

The role of the adaptor protein downstream of tyrosine kinase 1 (DOK1) in glioma cell motility
by: Barrett, A.
Published: (2014)

Novel biomarkers for the monitoring of chronic heart failure
by: Piper, Susan Elizabeth
Published: (2017)

The role of Nox2 containing NADPH oxidase in hypertensive heart disease
by: Chaubey, Sanjay
Published: (2013)

Understanding the role of inflammation in coronary heart disease patients with and without depression
by: Nikkheslat, Naghmeh
Published: (2014)

Repair of a wounded heart : an investigation into the effects of aggregation on the differentiation of stem cells to cardiomyocytes
by: Self, Magdalen Romany Rowen
Published: (2010)

Electrophysiological and pharmacological investigations concerning the possible arrhythmogenic action of free fatty acids on the heart
by: Cowan, J. Campbell
Published: (1977)

MicroRNAs play a role in human embryonic stem cell differentiation into endothelial cells
by: Luo, Zhenling
Published: (2011)

Kinetic characterisation of disease causing mutations in the embryonic and ß-cardiac myosin motor domain
by: Walklate, Jonathan
Published: (2016)

The roles of genetics and glycaemic control in the development of LVH and Heart Failure in Type 2 Diabetes
by: Parry, Helen
Published: (2015)

Characterisation of contraction and pharmacological response of cardiomyocytes derived from mouse and human embryonic stem cells
by: Martins, Marta Sofia Dias de Brito
Published: (2009)

Physical activity and cardiorespiratory fitness in adults with newly-diagnosed type 2 diabetes : associations with glycaemic control and cardiovascular risk factors
by: Fitzsimons, Kate J.
Published: (2009)

The role of PGC-1a in the transcriptional regulation of energy homeostasis in cardiac hypertrophy and heart failure
by: Ashrafian, Houman
Published: (2009)

Roles and mechanisms of action of the L-cysteine cystathionine-gamma-lyase hydrogen sulphide pathway in the heart
by: Elsey, David Jonathan
Published: (2009)

Inhibition of kinin metabolism and the role of the vascular B₁ kinin receptor in patients with congestive heart failure
by: Cruden, Nicholas Le May
Published: (2008)

To establish the role of mutations in c-KIT tyrosine kinase in the pathogenesis and therapy of core-binding factor-related acute myeloid leukaemia (AML)
by: Tinsley, S. P.
Published: (2014)

Investigating the role of Rac1 in cardiovascular development
by: Dodds, Rebecca
Published: (2017)

Protein kinase Ca in bone eevelopment, thrombopoiesis and thrombosis
by: Williams, Christopher M.
Published: (2010)

'What the brain tells the heart' anxiety, stress and the central control of the heart
by: Green, J.
Published: (1978)

Functional RNAi analysis of novel regulators of adhesion with further characterisation of the role of LZTFL1 in keratinocytes and heart disease
by: Bruche, Susann
Published: (2014)

The pulmonary endothelium contributes to inflammation in chronic heart failure : the role of mechanical strain and bone morphogenetic protein-9
by: Park, John E. S.
Published: (2010)

Diabetes and heart failure
by: MacDonald, Michael Ross
Published: (2011)

Congestive heart failure
by: Burton, G. E.
Published: (1946)