Investigating the role of WWP2 ubiquitin ligase isoforms in TGFβ-dependent oncogenic signalling
Ubiquitination is a post-translational modification involving the attachment of ubiquitin molecules onto target substrates. The most common function of ubiquitination is proteasomal degradation, which is commonly facilitated by the ubiquitination of target proteins at Lys-48. E3 ligases are crucial...
Main Author: | Yim, Hiu |
---|---|
Published: |
University of East Anglia
2017
|
Subjects: | |
Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.743337 |
Similar Items
-
Roles of the HECT-Type Ubiquitin E3 Ligases of the Nedd4 and WWP Subfamilies in Neuronal Development
by: Hsia, Hung-En
Published: (2015) -
Smad7 Binds Differently to Individual and Tandem WW3 and WW4 Domains of WWP2 Ubiquitin Ligase Isoforms
by: Lloyd C. Wahl, et al.
Published: (2019-09-01) -
Decoding the structure WWP2 in the TGFβ signalling pathway
by: Wahl, Lloyd
Published: (2016) -
Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled
by: Thomas Mund, et al.
Published: (2015-01-01) -
Elucidating ubiquitin recognition by the HECT-type ubiquitin ligase HUWE1
by: Mony Nair, Rahul
Published: (2021)