The CD8-mediated optimisation of the antigen specific T-cell response
CD8+ T-cells target infected and dysregulated cells for deletion. Failure of this response can result in persistent challenge, such as cancer or chronic infection. CD8+ T-cells recognize peptides in the context of major histocompatibility complex class I (MHCI) molecules on the surface of host cells...
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Cardiff University
2017
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.742851 |