Linking the structure of alpha-synuclein oligmers to function in Parkinson's disease

Misfolding and aggregation of alpha-synuclein (a-syn) are associated with a range of neurological disorders, including Parkinson's disease (PD). Fibrillar, insoluble aggregates of a-syn, known as Lewy bodies (LBs) are deposited in the substantia nigra and are a pathological hallmark of PD. a-sy...

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Bibliographic Details
Main Author: Illes-Toth, Timea E.
Other Authors: Smith, David ; Dalton, Caroline
Published: Sheffield Hallam University 2013
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.741439