CNS endothelium expression of ADAM-17 and its role in multiple sclerosis pathogenesis

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) characterised by focal lesions of inflammation and demyelination, with subsequent axonal damage. Various factors contribute to the pathogenesis of MS, including the breakdown of the blood-brain barrier (BBB), and in...

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Bibliographic Details
Main Author: Hurst, Louise Anne
Other Authors: Woodroofe, Nicola ; Bunning, Rowena
Published: Sheffield Hallam University 2009
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.741394