Asymmetric Michael-initiated ring closing reactions promoted by hydrogen bonding organocatalysis and the synthesis of cannabinoid metabolites

Hydrogen bonding organocatalysis has been used to develop two novel asymmetric Michael-initiated ring-closing reactions, reported herein. A reaction between vinyl cyanosulfones and bromomalonates, promoted by a novel cupreine organocatalyst, yielded highly substituted cyciopropanes as single diaster...

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Bibliographic Details
Main Author: Aitken, Lewis Scott
Published: University of Reading 2018
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.741110