Effect of DNMT3B expression on the human pluripotent stem cell methylome

Reprogramming of somatic cells into induced pluripotent stem cells is accompanied by extensive changes in gene expression and epigenetic marks. The single genotype human pluripotent stem cell (hPSC) model system developed in this study overcomes the experimental variability resulting from cell line...

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Bibliographic Details
Main Author: Shukla, Pooja
Published: University of Nottingham 2015
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738337