A study of allelic imbalance in human breast cancer

The analysis of loss of heterozygosity (LOH) in tumours can be used to map candidate sites of tumour-suppressor genes in the human genome. A panel of breast cancer patients was assembled as pairs of tumour and lymphocyte DNA samples and LOH studies carried out by Southern hybridization with polymorp...

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Bibliographic Details
Main Author: Loupart, Marie-Louise
Published: University of Leicester 1993
Subjects:
572
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.737444