Detection of subtle immune defects in individuals at risk of pneumococcal disease

Immunocompromised individuals are at increased risk of developing invasive pneumococcal disease (IPD). We have previously shown that IPD sufferers have defective in vitro B-cell responses to a T-independent antigen mimic (αδdex), relative to healthy controls. We hypothesized that similar defects wil...

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Bibliographic Details
Main Author: Asani, Furaha Florence
Other Authors: de Silva, Thushan ; Heath, Andy ; Dockrell, David ; Marriott, Helen ; Foster, Rachel ; Snowden, John
Published: University of Sheffield 2017
Subjects:
610
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.736544