Targeting the Hedgehog pathway in disease : a structural biology approach
The Hedgehog (Hh) pathway is a morphogen pathway essential for proper embryonic development of all bilaterians that remains active in adults where it contributes to tissue homoeostasis. Malfunction of the pathway results in developmental defect, while constitutive activation was correlated with mult...
Main Author: | Sefer, Lea |
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Other Authors: | Siebold, Christian ; Biggin, Philip |
Published: |
University of Oxford
2017
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.736129 |
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