Targeting the Hedgehog pathway in disease : a structural biology approach

The Hedgehog (Hh) pathway is a morphogen pathway essential for proper embryonic development of all bilaterians that remains active in adults where it contributes to tissue homoeostasis. Malfunction of the pathway results in developmental defect, while constitutive activation was correlated with mult...

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Bibliographic Details
Main Author: Sefer, Lea
Other Authors: Siebold, Christian ; Biggin, Philip
Published: University of Oxford 2017
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.736129