Autophagy-dependent generation of free fatty acids is essential for normal neutrophil differentiation by guiding an energy-metabolic switch

Neutrophils are critical and short lived mediators of innate immunity that require constant replenishment. Their differentiation in the bone marrow requires extensive cytoplasmic and nuclear remodeling, but the processes governing these energy-consuming changes are unknown. While previous studies sh...

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Bibliographic Details
Main Author: Riffelmacher, Thomas
Other Authors: Simon, Anna K. ; Jacobsen, Sten Eirik W.
Published: University of Oxford 2017
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.736036