Studies towards the biomimetic synthesis of resorcylic acid lactones
Resorcylic acid lactones (RALs) are a biologically important and structurally interesting class of natural products. Recently the Barrett group has developed a novel, biomimetic strategy to access RALs that bypasses many common inefficiencies inherent to more classical synthetic approaches. The focu...
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Imperial College London
2015
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.733044 |
| Summary: | Resorcylic acid lactones (RALs) are a biologically important and structurally interesting class of natural products. Recently the Barrett group has developed a novel, biomimetic strategy to access RALs that bypasses many common inefficiencies inherent to more classical synthetic approaches. The focus of this thesis consists of a synthetic study of the RALs radicicol and paecilomycin B that utilised this methodology. |
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