N.M.R. structural studies and modelling of modular proteins

This thesis focuses on structural studies of the fibronectin type 1 module (F1) of tissue-type plasminogen activator (t-PA) and the N-terminal src homology 2 (SH2) module of the p85α subunit of phosphatidylinositol-3-OH kinase (PI3-kinase). t-PA plays a key role in the dissolution of blood clots. It...

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Bibliographic Details
Main Author: Downing, Anna Kristina
Published: University of Oxford 1993
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.730626