Design and utilisation of a poised fragment library against epigenetic proteins

Fragment based drug discovery has become an important method in biomedical research. In particular, it has enabled academic researchers to develop drug-like compounds and chemical probes which can be used for target validation. Recent developments at Diamond Light Source have made X-ray crystallogra...

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Bibliographic Details
Main Author: Cox, Oakley Benjamin
Other Authors: Von Delft, Frank ; Brennan, Paul
Published: University of Oxford 2016
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.729925

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