Expression and purification of the multidrug resistance protein P-glycoprotein and high-throughput assay development for drug discovery
P-glycoprotein is an ATP binding cassette transporter that is involved in multidrug resistance in diseases such as cancer. It is a protein that can bind and transport a wide variety of unrelated hydrophobic compounds. Several polymorphisms of human P-glycoprotein have been associated with altered ex...
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University of Manchester
2017
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.728036 |