Design and synthesis of benzofused biaryl polyamides as G-quadruplex targeting agents
Guanine-rich nucleic acids can fold into distinctive four-stranded G-quadruplex structures which are found in telomeric DNA repeats, as well as in sequences in promoter and other regulatory regions of genes, especially those involved in cellular proliferation. Small molecules that can selectively bi...
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King's College London (University of London)
2017
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.727019 |