Characterisation of transgene expression in human embryonic stem cells by combining gene targeting and site-specific recombination

Predictable levels of transgene expression will be essential for full exploitation of human ES cells (hES) in basic research and medicine. In practice however, transgene expression in mammalian cells is often found to be silenced, low or variegated presenting a serious drawback in this area of resea...

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Bibliographic Details
Main Author: Di Domenico, Alexandra Isabelle
Published: University of Edinburgh 2007
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.726406