Genome editing approaches for development of pan-population immunotherapies
Background - T-cell based immunotherapy is the greatest recent breakthrough in cancer treatment, and can induce complete lasting remission. T-cells are capable of responding to a vast diversity of antigens via their hypervariable T-cell receptor (TCR). However, current immunotherapies rely on αβ T-c...
Main Author: | Legut, Mateusz |
---|---|
Published: |
Cardiff University
2017
|
Subjects: | |
Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.725710 |
Similar Items
-
ROR1 as a target for cancer immunotherapy
by: Paredes Moscosso, Solange Rosa
Published: (2017) -
Development of c-Met targeted chimeric antigen receptor T-cell immunotherapy for malignant pleural mesothelioma
by: Thayaparan, Thivyan
Published: (2016) -
Cellular and vaccination-based immunotherapy of acute myeloid leukaemia
by: Krishnamurthy, Pramila
Published: (2014) -
Investigation of pan-HDAC inhibitor Vorinostat and novel microtubule targeting agent PBOX 15 as a potential therapeutic combinational approach for chronic lymphocytic leukaemia
by: Jameson, Warren Randall
Published: (2012) -
In vitro generation of cytotoxic T cells with potential for adoptive tumour immunotherapy
by: Khalaf, Wafaa Seifalnaser Sedik
Published: (2017)