The role of FKBPL and its peptide derivatives in targeting stemness
FKBPL is a secreted protein with well-established anti-angiogenic activity and a novel therapeutic peptide, ALM201, derived from the protein has entered Phase l/ll clinical trial in ovarian cancer patients. Ovarian cancer is the most lethal gynaecologic cancer with a high incidence of recurrent chem...
Main Author: | Annett, Stephanie Louise |
---|---|
Published: |
Queen's University Belfast
2017
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.725332 |
Similar Items
-
Targeting treatment resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01
by: McClements, Lana
Published: (2014) -
Modulation of the anti-angiogenic protein FKBPL : implications for a host of diseases, including cancer
by: Bennett, Rachel
Published: (2015) -
Evaluating the prognostic and predictive potential of FKBPL and associated proteins as biomarkers in breast and ovarian cancer
by: Nelson, Laura
Published: (2015) -
Auger electron radionuclide therapy utilising F3 peptide to target the nucleolus
by: Hillyar, Christopher
Published: (2015) -
The role of cancer stem cells in osteosarcoma
by: Jenks, Andrew
Published: (2014)