Statistical issues in the design and analysis of early phase proof of concept clinical trials in rheumatoid arthritis
Introduction: Rheumatoid Arthritis (RA) is a chronic inflammatory disorder that typically affects joints of the body such as knees, hands and feet. The prevalence of RA is around 1% in the general population and the incidence rate is about 41 per 100,000 persons per year. The use of adaptive designs...
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University of Sheffield
2017
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.722791 |