Identifying mechanisms of androgen receptor variant regulation in models of castrate resistant prostate cancer

Current treatment options for the management of prostate cancer (PC) attempt to abrogate androgen receptor (AR) signalling by reducing circulating androgens in addition to inhibiting AR-ligand binding, collectively termed androgen deprivation therapy (ADT). Although initially efficacious, most patie...

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Bibliographic Details
Main Author: Jones, Dominic Louis
Published: University of Newcastle upon Tyne 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.722578