Gain and loss of progranulin have opposite effects on autophagy
Progranulin (PGRN) is a widely expressed cysteine-rich, secreted glycoprotein with growth factor-like properties. PGRN is involved in both metabolism and neurodegeneration. It has recently emerged as an important regulatory adipokine of glucose metabolism and insulin sensitivity. Individuals with ob...
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Open University
2017
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.722525 |