Synthetic studies on the azinothricin family of antitumour antibiotics
A first synthesis of the acyl side chain of azinothricin and a second-generation route to the A83586C side chain is described in this thesis. The successful strategy was based on an asymmetric aldol reaction, a stereoselective Roush-type crotylboration and a Trost asymmetric allylic alkylation react...
| Main Author: | |
|---|---|
| Published: |
University College London (University of London)
2007
|
| Subjects: | |
| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.722226 |