Self-optimisation of automated continuous reactors

The optimisation of problematic reaction steps in the synthesis of a drug compound is crucial for pharmaceutical process development. In recent traditions, this has carried out using design of experiments (DoE), which shows the key reaction variables and provides optimum reaction conditions. The pro...

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Bibliographic Details
Main Author: Holmes, Nicholas
Other Authors: Bourne, Richard ; Blacker, John
Published: University of Leeds 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718807