Isolation of sensory neurons in vitro and generation of a conditional inducible transgenic mouse line against nerve growth factor (NGF) receptors to investigate the role of NGF in pain

Nerve growth factor (NGF) is a known factor in the development of persistent pain, a condition which affects approx. 20% of the UK population. Current therapeutics available for pain exhibit limited effectiveness and therefore better targeted and more effective therapeutics are essential. Clinical t...

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Bibliographic Details
Main Author: Kelleher, Jayne Hannah
Other Authors: Raouf, Ramin Kateb ; McMahon, Stephen Brendan
Published: King's College London (University of London) 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.718627