Modulation of intracellular ATP influences seizure activity via the activity-dependent release of adenosine
A large number of patients with epilepsy have drug-resistant seizures. Therefore, there is a need for the development of new therapies. The purine nucleoside adenosine is an endogenous anticonvulsant that acts to supress neuronal excitability via adenosine A1 receptors. The aim of this thesis was to...
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University of Warwick
2016
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.714932 |