Deacetylation of GD3A as a potential therapeutic strategy for paediatric medulloblastoma

Medulloblastoma survivors frequently suffer from low quality of life as a result of aggressive treatment. New treatments are urgently needed to reduce down-stream sequelae. GD3, an oncofoetal ganglioside, has roles in embryonic brain development and is commonly modified to 9-O-acetyl GD3 (GD3<sup...

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Bibliographic Details
Main Author: Mather, Rebecca Louise
Other Authors: Pilkington, Geoffrey John ; Fillmore, Helen Louise
Published: University of Portsmouth 2016
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.714197