Identification and mechanistic study of novel drug metabolites by LC-MS
Understanding the metabolic fate of drug candidates in vitro and in vivo is a key component of drug development. Structural characterisation of drug candidate metabolites is important early in drug discovery to identify unwanted metabolic liabilities such as reactive, active, toxic or human specific...
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Sheffield Hallam University
2016
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713505 |