Genetic risk and resilience for Alzheimer's disease : the effect of the three APOE alleles on brain function across life
The human apolipoprotein E (APOE) gene has three alleles (ε2, ε3 and ε4). Relative to the most common ε3 allele, ε4 is associated with a higher risk of developing sporadic late-onset Alzheimer's disease (AD) whereas ε2 is believed to confer a protection to AD. Because of ε4's close associa...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
University of Oxford
2015
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.712418 |