Expression of growth factor receptors by haematopoietic stem and progenitor cells

The mechanisms that govern the lineage commitment of haematopoietic stem and progenitor cells (HSPCs) have been a topic of debate since the 1960s. Two models of lineage commitment have been described; a permissive model, in which haematopoietic growth factors (HGFs) stimulate proliferation and survi...

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Bibliographic Details
Main Author: Mooney, Ciarán James
Published: University of Birmingham 2017
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.707678