Investigating the impact of OCT transporter genotype on metformin-induced vitamin B12 deficiency

Metformin is the first-line therapy for the treatment of Type 2 Diabetes Mellitus (T2DM) and is the most widely prescribed anti-diabetic drug in the world. A common and potentially hazardous side-effect of metformin treatment is vitamin B12 deficiency. OCT1 (SLC22A1) and OCT2 (SLC22A2) are highly po...

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Bibliographic Details
Main Author: Green, L. A.
Other Authors: Pirmohamed, M. ; Park, B. ; Antoine, D.
Published: University of Liverpool 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.706764