The role of complement and monocytes in antineutrophil cytoplasmic antibody associated vasculitis

Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a multi-systemic disease with autoantibody generation to myeloperoxidase (MPO) and proteinase 3 (PR3), components of neutrophils and monocytes. It is widely believed that ANCA are pathogenic. The most convincing evidence for t...

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Bibliographic Details
Main Author: Popat, Reena Jayantilal
Published: King's College London (University of London) 2016
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.700763