The synthesis of biologically active guanidines

Several new alkyl (147, 161 and 167) and alkoxy-methyl derivatives (171, 175) were prepared as analogues of the anti-tumour agent tirapazamine (38). These were prepared in an attempt to couple them to the pro-drug delivery agent 52. The bicyclic guanidine natural product monalidine A (186) was prepa...

Full description

Bibliographic Details
Main Author: Harper, Philip Mark
Published: Bangor University 2016
Subjects:
547
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.698936

Similar Items