Dissecting the intricacies of sterol dysregulation in Huntington's disease
Background: Huntington’s disease (HD) is a devastating neurodegenerative condition, caused by an expanded polyglutamine tract in the Huntingtin (Htt) protein. HD is manifested by personality changes, movement disorders and/or dementia. Prior evidence exists for sterol dysregulation in HD models, obs...
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University of Leicester
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.697426 |