Inhaled 99mTc-sestamibi clearance from lungs and its relation to the expression of P-glycoprotein and Multidrug Resistance Protein-1
P-glycoprotein (P-gp) and Multidrug Resistance Protein (MRP1) are the key cellular drug efflux transporters in a range of tissues and the radiopharmaceutical 99mTc-sestamibi has been demonstrated to be a substrate for both transporters in a number of in vivo and in vitro studies. The elimination rat...
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King's College London (University of London)
2016
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.695785 |