Helicase activation mechanisms during initiation of DNA replication

This thesis provides new insights into the recruitment mechanisms of factors to replicative origins that are important for helicase activation during initiation of DNA replication in budding yeast. DNA replication origins are recognised by the Origin Recognition Complex (ORC), which recruits, during...

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Bibliographic Details
Main Author: Tognetti, Silvia
Other Authors: Speck, Christian
Published: Imperial College London 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.695499