Investigating the role of the ribonuclease DIS3 in haematological cancers

Whole genome sequencing has recently identified DIS3 as a novel tumour suppressor gene in multiple myeloma. DIS3 is a conserved RNA exonuclease and catalytic subunit of the exosome, a protein complex involved in the 3’ to 5’ degradation and processing of messenger RNA and small RNAs. Messenger RNA p...

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Bibliographic Details
Main Author: Robinson, Sophie Rebecca
Published: University of Brighton 2016
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694870

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