Investigating the role of the ribonuclease DIS3 in haematological cancers
Whole genome sequencing has recently identified DIS3 as a novel tumour suppressor gene in multiple myeloma. DIS3 is a conserved RNA exonuclease and catalytic subunit of the exosome, a protein complex involved in the 3’ to 5’ degradation and processing of messenger RNA and small RNAs. Messenger RNA p...
Main Author: | |
---|---|
Published: |
University of Brighton
2016
|
Subjects: | |
Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694870 |