Interactions of microRNA27a and prohibitin in the androgen signalling pathway
Prohibitin (PHB) is a highly conserved, multi-functional protein that acts as a tumour suppressor and androgen receptor (AR) corepressor. We found that downregulation of PHB by androgens is required to drive androgen-dependent prostate cancer cell growth. This effect can be mimicked through the use...
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Imperial College London
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.693951 |