Functional role of calreticulin in MHC class I antigen presentation
MHC class I antigen presentation to cytotoxic T cells (CTLs) is critically important to maintain immunity against pathogens and tumour-transformed cells. In this conventional class I pathway, peptides generated from endogenous proteins in the cytosol by proteasomes are transported into the ER lumen...
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University College London (University of London)
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.692563 |