The role of complement iC3b in dense deposit disease

Dense deposit disease (DDD) is a rare, progressive and incurable kidney disease characterized by complement C3 accumulation along the glomerular basement membrane (GBM). It is the prototypical form of C3 glomerulopathy, which comprises renal disorders due to excessive C3 activation via the alternati...

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Bibliographic Details
Main Author: Barbour, Thomas David
Other Authors: Pickering, Matthew ; Botto, Marina
Published: Imperial College London 2015
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.689091